Clinical And Metabolic Characteristics Of The Studied Groups

3.1. Clinical and metabolic characteristics Demographic variables and clinical characteristics of the studied groups are shown in Table 1. There was no significant difference in age, body mass index between the studied groups. Meanwhile, there were statistically significant increase in disease duration; TG, TC, FBG levels and HbA1C percentage in diabetic cases when compared to their allied control group with higher values were for macro-albuminuria T2DM group. LDL-C and HDL-C levels showed statistically significant difference in diabetic cases when compared to their allied control group but with no difference between micro and macro albuminuria T2DM groups. Serum urea, creatinine and UACR were statistically significantly higher in T2DM cases when compared to their allied control group and normo-albuminuria T2DM groups with higher values were for macro-albuminuria T2DM group (Table 1). 3.2. Immune/ inflammatory status and tubular damage This current study revealed statistically significant increase in plasma ox-LDL level and up-regulation of TLR4 expression in T2DM cases when compared to their allied control group with higher values were for macro-albuminuria T2DM group. Meanwhile, plasma omentin1 level was statistically significantly decreased in T2DM cases than their allied controls with lower values were for macro-albuminuria T2DM group. This current study revealed statistically significant increase in urinary LCN2 level in T2DM cases than their allied control groupShow MoreRelatedIs Withaferin A, A Magic Bullet For Metabolic Syndrome?1435 Words   |  6 PagesIs Withaferin A, a magic bullet for metabolic syndrome? 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